一、个人简况
左亚运，男，汉族，中共党员，1990年出生于湖南衡阳，博士。
二、学习及工作经历
1、2019.07至今，西北农林科技大学植物保护学院，教师。
2、2015.09-2019.06，南京农业大学植物保护学院学习，获博士学位，期间主要从事甜菜夜蛾对甲维盐和氯虫苯甲酰胺抗性机制的研究。
3、2012.09~2015.07，西北农林科技大学植物保护学院，获硕士学位，期间主要从事禾谷缢管蚜抗性机制的研究。
4、2008.09~2012.07，山东农业大学植物保护学院学习，获学士学位。
三、目前主要研究方向
方向一：以鳞翅目害虫为研究对象，利用CRISPR/Cas9技术、QTL定位技术、生物信息等手段研究以及其对化学杀虫剂的抗性机理，为害虫综合治理提供理论依据。
方向二：通过培育植物源农药抗性品系，通过反向遗传学的手段寻找植物源农药的作用靶标，为新农药的创制提供基础。
四、承担课题项目
国家青年基金 甜菜夜蛾多杀菌素靶标抗性等位基因多样性检测及代谢抗性基因鉴定 （32001941）
博后基金 miRNA 调控 SeCYP9A9 介导甜菜夜蛾对毒死蜱抗性的分子机制
科研启动费 甜菜夜蛾nAChRα6基因突变与多杀菌素抗性的关系
五、已发表论文
1 Zuo, Y. Y., Xue, Y. X., Wang, Z. Y., Ren, X., Y. D., Aioub, A. A. A., Yang, Y, H., & Hu, Z. N. (2021). Knockin of the G275E mutation of the nicotinic acetylcholine receptor (nAChR) α6 confers high levels of resistance to spinosyns in Spodoptera exigua . Insect science, http://doi.org/10.1111/1744-7917.12922
2 Zuo, Y. Y., Shi, Y., Zhang, F., Guan, F., Zhang, J., Feyereisen, R., . & Wu, Y. (2021). Genome mapping coupled with CRISPR gene editing reveals a P450 gene confers avermectin resistance in the beet armyworm. PLoS genetics, 17(7), e1009680.
3 Zuo, Y. Y., Xue,Y. X., Lu, W. J., Chen, M. H., Wu, Y. D., Yang, Y, H., & Hu, Z. N. (2020). Functional validation of nicotinic acetylcholine receptor (nAChR) α6 as a target of spinosyns in Spodoptera exigua utilizing the CRISPR/Cas9 system. Pest Management Sci ence , 76.
4 Zuo, Y. Y., Ma, H. H., Lu, W. J., Wang, X. L., Wu, S. W., Nauen, R., & Yang, Y. H. (2020). Identification of the ryanodine receptor mutation I4743M and its contribution to diamide insecticide resistance in Spodoptera exigua (Lepidoptera: Noctuidae). Insect science . 27, 791–800
5 Zuo, Y. Y., Huang, J. L., Wang, J., Feng, Y., Han, T. T., Wu, Y. D., & Yang, Y. H. (2018). Knockout of a P‐glycoprotein gene increases susceptibility to abamectin and emamectin benzoate in Spodoptera exigua . Insect molecular biology, 27(1), 36-45.
6 Zuo, Y. Y., Wang, H., Xu, Y., Huang, J., Wu, S., Wu, Y. D., & Yang, Y. H. (2017). CRISPR/Cas9 mediated G4946E substitution in the ryanodine receptor of Spodoptera exigua confers high levels of resistance to diamide insecticides. Insect biochemistry and molecular biology , 89 , 79-85.
7 Zuo, Y. Y., Wang, K., Zhang, M., Peng, X., Piñero, J. C., & Chen, M. (2016). Regional susceptibilities of Rhopalosiphum padi (Hemiptera: Aphididae) to ten insecticides. Florida Entomologist, 269-275
8 Zuo, Y. Y., Peng, X., Wang, K., Lin, F., Li, Y., & Chen, M. H. (2016). Expression patterns, mutation detection and RNA interference of Rhopalosiphum padi voltage-gated sodium channel genes. Scientific reports, 6, 30166.
9 Zuo, Y. Y., Wang, K., Lin, F., Li, Y., Peng, X., Piñero, J. C., & Chen, M. H. (2016). Sublethal effects of indoxacarb and beta-cypermethrin on Rhopalosiphum padi (Hemiptera: Aphididae) under laboratory conditions. Florida Entomologist , 445-450.
10 Aioub, A. A. A., Zuo, Y. Y., Aioub, A. A. A., & Hu., Z. N. (2021). Biochemical and phytoremediation of Plantago major L. to protect tomato plants from the contamination of cypermethrin pesticide. Environmental Science and Pollution Research. https://doi.org/10.1007/s11356-021-13853-2
11 Hao, H. H., Zuo, Y. Y., Fang, J. M., Sun, A. Q., Aioub, A. A. A., & Hu., Z. N. (2021). Transcriptome Analysis of Aedes albopictus (Diptera: Culicidae) Larvae Exposed With a Sublethal Dose of Haedoxan A. Journal of Medical Entomology , doi: 10.1093/jme/tjab089.
12 Aioub, A. A. A., Zuo, Y. Y., Li, Y. K., Qie, X. T., Zhang, X. X., Essmat, N., Wu, W. J., & Hu., Z. N. (2020). Transcriptome analysis of Plantago major as a phytoremediator to identify some genes related to cypermethrin detoxification.
13 Wang, J. , Ma, H. , Zuo, Y. Y., Yang, Y. H., & Wu, Y. D. (2020). CRISPR‐mediated gene knockout reveals nicotinic acetylcholine receptor (nAChR) subunit α6 as a target of spinosyns in H elicoverpa armigera. Pest Management Science . DOI: 10.1002/ps.5889
14 Huang, J. L., Xu, Y. J., Zuo, Y. Y., Yang, Y. H., Tabashnik, B. E. & Wu, Y. D. (2020). Evaluation of five candidate receptors for three bt toxins in the beet armyworm using CRISPR-mediated gene knockouts. Insect Biochemistry and Molecular Biology , 121.
15 Wang, J., Zuo, Y. Y., Li, L. L., Wang, H., Liu, S. Y., Yang, Y. H., & Wu, Y. D. (2019). Knockout of three aminopeptidase N genes does not affect susceptibility of Helicoverpa armigera larvae to Bacillus thuringiensis Cry1A and Cry2A toxins. Insect science . DOI: 10.1111/1744-7917.12666
16 Wang, J., Zhang, H. N., Wang, H. D., Zhao, S., Zuo, Y. Y., Yang, Y. H. & Wu, Y. D. (2016). Functional validation of cadherin as a receptor of Bt toxin Cry1Ac in Helicoverpa armigera utilizing the CRISPR/Cas9 system. Insect biochemistry and molecular biology , 76, 11-17.
17 Zhang M., Qiao X., Li Y. T., Fang B., Zuo Y. Y., Chen M. H.. (2016) Cloning of eight Rhopalosiphum padi (Hemiptera: Aphididae) nAChR subunit genes and mutation detection of the β1 subunit in field samples from China. Pesticide Biochemistry and Physiology , 132: 89-95.
18 Wang K., Peng X., Zuo Y. Y., Li Y. T., Chen M. H.. (2016) Molecular cloning, expression pattern and polymorphisms of NADPH-cytochrome P450 reductase in the bird cherry-oat aphid Rhopalosiphum padi (L.). PLoS ONE , 11: e0154633.
19 .Duan X. L., Men Q. L., Li Y. T., Zuo Y. Y., Zhang M, Qiao X. F., Chen M. H. (2016) Microsatellite analysis revealed limited gene flow among populations of an invasive species Cydia pomonella (Lepidoptera: Tortricidae) in two isolated regions of a corridor area in China: knowledge on the population genetics for the sterile insect technique. Florida Entomologist , 99(s1): 23-29.
20 左亚运，李晓叶，李玉婷，王康，乔宪凤，陈茂华。禾谷缢管蚜水通道蛋白基因RpAQP1的克隆、分子特性和表达分析，植物保护学报，2014，41（6）：657-664。
21 左亚运，潘红燕， 陈茂华*。禾谷缢管蚜田间种群Ace1基因选择性剪切研究。应用昆虫学报，2014，51（6）：1488-1495。
22 段辛乐，乔宪凤，彭雄，左亚运，刘高鸣，陈茂华。我国禾谷缢管蚜微卫星位点扩增稳定性及遗传多样性。植物保护学报，2015，42（3）：297-303.
23 林芳菲，左亚运，赵奇，段辛乐，李玉婷，陈茂华。禾谷缢管蚜阳离子通道RSC1的克隆、分子特性及诱导表达分析。昆虫学报，2016，59（7）：716-723.
六、联系方式
陕西杨凌，西北农林科技大学植保学院，邮编：712100，
Email：zuoyayun0734@163.com; yayunzuo@nwafu.edu.cn
